Characteristics of patients with or without organ failure
| Characteristic | All patients (n=639) | Organ failure n=240 (38%) | No organ failure n=399 (62%) | P values |
| Age (years) | 58 (45–70) | 61 (50–71) | 56 (43–70) | 0.003* |
| Male sex, no. (%) | 398 (62) | 158 (66) | 240 (60) | 0.15† |
| ASA class on admission (%) | <0.001‡ | |||
| I | 202 (32) | 59 (25) | 143 (36) | |
| II | 347 (54) | 131 (55) | 216 (54) | |
| III | 90 (14) | 50 (21) | 40 (10) | |
| Pre-existent chronic disease, no. (%) | 28 (4) | 20 (8) | 8 (2) | <0.01† |
| Pre-existent diabetes mellitus, no. (%) | 52 (8) | 20 (8) | 32 (8) | 0.89† |
| Dialysis prior to admission, no. (%) | 9 (1) | 4 (2) | 5 (1) | 0.67† |
| Body mass index (kg/m2)§ | 27 (25–31) | 27.1 (25–31.1) | 26.8 (25–30.7) | 0.59* |
| Aetiology (%) | 0.91† | |||
| Gallstones | 304 (48) | 114 (48) | 190 (48) | |
| Alcohol abuse | 150 (24) | 54 (23) | 96 (24) | |
| Other | 63 (10) | 26 (11) | 37 (9) | |
| Unknown | 122 (19) | 46 (19) | 76 (19) | |
| Predicted severity | ||||
| APACHE II score¶ | 8 (5–11) | 9 (6–13) | 7 (4–10) | <0.001* |
| Modified Glasgow Score¶ | 3 (2–5) | 4 (3–5) | 3 (2–4) | <0.001* |
| Highest C reactive protein 48 hours after admission** | 291 (±130) | 284 (±134) | 295 (±127) | 0.24* |
| CT severity index | 4 (4–8) | 6 (4–10) | 4 (4–6) | <0.001* |
| Pancreatic parenchymal necrosis, no. (%) | 324 (51) | 163 (68) | 161 (40) | <0.001† |
| Extent of pancreatic necrosis, no. (%) | <0.001† | |||
| <50% | 530 (83) | 170 (71) | 360 (90) | |
| >50% | 109 (17) | 70 (29) | 39 (10) | |
| Extrapancreatic necrosis alone, no. (%) | 315 (49) | 77 (32) | 238 (60) | <0.001† |
| Hospital stay in days | 28 (14–66) | 64 (31–106) | 19 (12–38) | <0.001* |
| ICU stays in days | 3 (0–22) | 22 (9–42) | 0 (0–0) | <0.001* |
| Infected pancreatic necrosis, no. (%) | 202 (32) | 132 (55) | 70 (18) | <0.001† |
| Any intervention (eg, catheter drainage, necrosectomy), no. (%) | 242 (38) | 177 (74) | 65 (16) | <0.001† |
| Timing intervention (catheter drainage or necrosectomy), days after admission | 29 (21–41) | 27 (25–31) | 38 (23–56) | 0.003* |
| Transferred from other hospital, no. (%) | 156 (24) | 95 (40) | 61 (15) | <0.001† |
Continuous variables are reported as mean±SD or median (IQR).
*Mann-Whitney U test.
†χ2 test.
‡Linear-by-linear χ2 association test.
§51% missing data.
¶<1% missing data.
**7% missing data.
ASA, American Society of Anesthesiologists; ICU, intensive care unit.