Table 1

Characteristics of patients with or without organ failure

CharacteristicAll patients (n=639)Organ failure n=240 (38%)No organ failure n=399 (62%)P values
Age (years)58 (45–70)61 (50–71)56 (43–70)0.003*
Male sex, no. (%)398 (62)158 (66)240 (60)0.15†
ASA class on admission (%)<0.001‡
 I202 (32)59 (25)143 (36)
 II347 (54)131 (55)216 (54)
 III90 (14)50 (21)40 (10)
Pre-existent chronic disease, no. (%)28 (4)20 (8)8 (2)<0.01†
Pre-existent diabetes mellitus, no. (%)52 (8)20 (8)32 (8)0.89†
Dialysis prior to admission, no. (%)9 (1)4 (2)5 (1)0.67†
Body mass index (kg/m227 (25–31)27.1 (25–31.1)26.8 (25–30.7)0.59*
Aetiology (%)0.91†
 Gallstones304 (48)114 (48)190 (48)
 Alcohol abuse150 (24)54 (23)96 (24)
 Other63 (10)26 (11)37 (9)
 Unknown122 (19)46 (19)76 (19)
Predicted severity
 APACHE II score¶8 (5–11)9 (6–13)7 (4–10)<0.001*
 Modified Glasgow Score¶3 (2–5)4 (3–5)3 (2–4)<0.001*
 Highest C reactive protein 48 hours after admission**291 (±130)284 (±134)295 (±127)0.24*
CT severity index4 (4–8)6 (4–10)4 (4–6)<0.001*
Pancreatic parenchymal necrosis, no. (%)324 (51)163 (68)161 (40)<0.001†
Extent of pancreatic necrosis, no. (%)<0.001†
 <50%530 (83)170 (71)360 (90)
 >50%109 (17)70 (29)39 (10)
Extrapancreatic necrosis alone, no. (%)315 (49)77 (32)238 (60)<0.001†
Hospital stay in days28 (14–66)64 (31–106)19 (12–38)<0.001*
ICU stays in days3 (0–22)22 (9–42)0 (0–0)<0.001*
Infected pancreatic necrosis, no. (%)202 (32)132 (55)70 (18)<0.001†
Any intervention (eg, catheter drainage, necrosectomy), no. (%)242 (38)177 (74)65 (16)<0.001†
Timing intervention (catheter drainage or necrosectomy), days after admission29 (21–41)27 (25–31)38 (23–56)0.003*
Transferred from other hospital, no. (%)156 (24)95 (40)61 (15)<0.001†
  • Continuous variables are reported as mean±SD or median (IQR).

  • *Mann-Whitney U test.

  • †χ2 test.

  • ‡Linear-by-linear χ2 association test.

  • §51% missing data.

  • ¶<1% missing data.

  • **7% missing data.

  • ASA, American Society of Anesthesiologists; ICU, intensive care unit.