Table 2

Brain imaging modalities

Imaging modalityDescription
 Positron emission tomographyMeasures regional glucose utilisation, cerebral blood flow (both measures of regional brain activity) and receptor occupancy.
 Arterial spin labellingCerebral blood flow.
 ElectroencephalogramCerebral electrical activity.
 MagnetoencephalographyMeasures magnetic fields produced by electrical activity of the brain.
 Magnetic resonance spectroscopyMeasures brain concentration of brain metabolites and neurotransmitters.
 Structural MRIProvides high spatial resolution and soft tissue contrasts to measure brain morphometry.
 Functional MRIMeasures brain activity by detecting changes in blood oxygenation and flow during rest or an evoked task.
 Diffusion tensor imagingAssesses the microstructure of white matter and anatomical connectivity and integrity.