Assessment at day 3 of corticosteroids | Chance of treatment failure* | Reference | ||
BO >8/day or BO 3–8/day and CRP >45 mg/L | 85% | Travis et al 1281 | ||
Mean stool frequency day 1–3 | Total: | Ho et al 1282 | ||
<4 | 0 | |||
4–6 | 1 | 0–1 | 11% | |
7–9 | 2 | 2–3 | 45% | |
>9 | 4 | ≥4 | 85% | |
Transverse colonic dilatation on abdominal X-ray ≥5.5 cm | 4 | |||
Albumin on admission <30 g/L | 1 | |||
Number of stools in 24 hours + (0.14×CRP (mg/L)) >8 | 72% | Lindgren et al 1283 | ||
CRP/albumin ratio >0.85 combined plus stool frequency >3 | 74% | Gibson et al 223 |
*Variably defined as failure of steroid therapy or risk of inpatient colectomy.