HLA-adjusted OR of cumulative virus detections in stool up to 1 year of age from a matched CDA case and control study
| Virus/serotype | OR (95% CI) | P value | Cases positive (n)† | Controls positive (n)† |
| Any virus | 0.68 (0.49 to 0.94) | 0.02 | 63 | 72 |
| HEV* | 0.97 (0.56 to 1.70) | 0.92 | 17 | 19 |
| HEV A | 1.65 (0.56 to 4.84) | 0.36 | 8 | 6 |
| CVA | 6.69 (0.70 to 63.79) | 0.1 | 8 | 2 |
| HEV B | 1.64 (0.77 to 3.53) | 0.2 | 12 | 8 |
| CVB | 1.85 (0.81 to 4.24) | 0.15 | 12 | 7 |
| Echovirus | 1.92 (0.68 to 5.45) | 0.22 | 9 | 6 |
| HAdV* | 0.69 (0.48 to 0.99) | 0.04 | 56 | 65 |
| HAdV A | 0.56 (0.13 to 2.36) | 0.43 | 3 | 3 |
| HAdV B | NA | NA | 1 | 3 |
| HAdV C | 0.72 (0.37 to 1.37) | 0.31 | 19 | 23 |
| HAdV F | 3.62 (0.70 to 18.88) | 0.13 | 10 | 5 |
| Astrovirus | 0.94 (0.42 to 2.11) | 0.89 | 15 | 18 |
| Norovirus | 1.10 (0.48 to 2.52) | 0.82 | 12 | 11 |
| Reovirus | 0.71 (0.03 to 18.69) | 0.84 | 1 | 1 |
| Rotavirus | NA | NA | 0 | 1 |
Total number of pairs with available stool samples is 79.
*Species and serotypes of HEV and HAdV are based on virome capsid mapping after Vipie genus taxonomy identification as follows: enterovirus capsid (VP1-4) repository includes CVA9, CVB1-6, Echovirus 6, 11, 18, 25 and 30. Adenovirus resource includes penton, hexon and fibre regions from prototypes AC_000007, X73487, JX423382, NC_010956, NC_001454 and KF303071.
†Number refers to the number of children having at least one viral sequence read in the stool.
CDA, coeliac disease autoantibody positivity; CVA, coxsackievirus A; CVB, coxsackievirus B; HAdV, human adenovirus; HEV, human enterovirus; NA, not applicable.