Cox multivariate analysis of the relationship between clinical and image variables and RFS
| Multivariate Cox models | |||
| Discovery cohort (n=713) | |||
| HR | 95% CI | P value | |
| Histopathology grading | |||
| Poorly/undifferentiated | 1 | ||
| Well/moderately | 0.811 | 0.585 to 1.125 | 0.21 |
| Unknown | |||
| T | |||
| T3 | 1 | ||
| T1/T2 | 0.516 | 0.240 to 1.111 | 0.09 |
| T4 | 1.696 | 1.255 to 2.292 | 0.0006 |
| N | |||
| N1 | 1 | ||
| N2 | 2.181 | 1.655 to 2.875 | 3.10E-08 |
| KRAS | |||
| Mutated | 1 | ||
| Wild type | 0.644 | 0.488 to 0.848 | 0.002 |
| DGMuneS | 1.989 | 1.373 to 2.881 | 0.0003 |
| C-index | 0.69 | ||
| AIC | 2567.345 | ||
AIC, akaike information criterion; KRAS, kirsten rat sarcoma viral oncogene homolog; RFS, relapse-free survival.