Site distribution of SD CRCs and advanced adenomas by cumulative f-Hb values over the initial two rounds and among subjects with a positive result at the second FIT
| Sum f-Hb μg/g FIT1 + FIT2 | CRC | Advanced adenoma | |||||
| Distal N % (95% CI) | Proximal N % (95% CI) | Total | Distal N % (95% CI) | Proximal N % (95% CI) | Distal + proximal N % (95% CI) | Total | |
| 0 | 20 | 15 | 35 | 148 | 88 | 21 | 257 |
| 57.1 (39.5 to 73.2) | 42.9 (26.8 to 60.5) | 57.6 (51.3 to 63.7) | 34.2 (28.5 to 40.4) | 8.2 (5.3 to 12.4) | |||
| 0. 1 – 3.9 | 23 | 32 | 55* | 192 | 85 | 17 | 294 |
| 41.8 (28.9 to 55.9) | 58.2 (44.2 to 71.1) | 65.3 (59.5 to 70.7) | 28.9 (23.9 to 84.5) | 5.8 (3.5 to 9.3) | |||
| 4 – 9.9 | 16 | 20 | 36 | 179 | 94 | 28 | 301 |
| 44.4 (28.3 to 61.7) | 55.6 (38.3 to 71.7) | 59.5 (53.7 to 65.0) | 31.2 (26.1 to 36.8) | 9.3 (6.4 to 13.3) | |||
| 10 – 14.9 | 21 | 4 | 25 | 88 | 59 | 14 | 161 |
| 84.0 (63.1 to 94.8) | 16.0 (5.3 to 36.9) | 54.7 (44.6 to 62.5) | 36.6 (29.3 to 44.6) | 8.7 (5.0 to 14.4) | |||
| 15 – 19.9 | 8 | 8 | 16 | 68 | 35 | 20 | 123 |
| 50.0 (25.5 to 74.5) | 50.0 (25.5 to 74.5) | 55.3 (46.1 to 64.2) | 28.5 (20.9 to 37.4) | 16.3 (10.5 to 24.2) | |||
| ≥ 20 | 15 | 6 | 21 | 53 | 40 | 18 | 111 |
| 71.4 (47.1 to 87.8) | 28.6 (12.2 to 52.3) | 47.7 (38.3 to 57.4) | 36.0 (27.3 to 45.8) | 16.2 (10.2 to 24.7) | |||
| Total | 103 | 85 | 188 | 728 | 401 | 118 | 1247 |
| 54.8 (47.4 to 62.0) | 45.2 (38.0 to 52.6) | 58.4 (55.6 to 61.1) | 32.2 (29.6 to 34.8) | 9.5 (7.9 to 11.3) | |||
| FIT + second test | 214 | 130 | 344† | 1152 | 557 | 279 | 1988 |
| 62.2 (56.8 to 67.3) | 37.8 (32.7 to 43.2) | 58.0 (55.7 to 60.1) | 28.0 (26.1 to 30.1) | 14.0 (12.6 to 15.7) | |||
*Information about site of the lesion is missing in one case.
†Information about site of the lesion is missing in six cases.
CRCs, colorectal cancers; f-Hb, faecal haemoglobin; FIT, faecal immunochemical test; SD, screen detected.