Table 2

Multivariable logistic regression analysis examining factors associated with LAMS-associated adverse events

Variable	OR	95% CI	P value
Multiple logistic regression analysis: Outcomevariable=AllLAMS-associated adverse events
Age: ≥60 vs <60 years	1.23	0.33 to 4.63	0.762
Gender: Male vs Female	0.91	0.24 to 3.49	0.888
Race: Caucasian vs Non-Caucasian	0.96	0.18 to 5.28	0.966
PFC type: Necrotic collection vs Pseudocyst	0.79	0.13 to 4.86	0.802
PFC size: ≤7 vs >7 cm	5.80	1.34 to 25.0	0.019
PFC location: Tail involved vs Tail not involved	1.15	0.21 to 6.40	0.871
Degree of necrosis: ≤40 vs>40%	1.52	0.30 to 7.61	0.608
Route of drainage: Proximal stomach vs Other	1.95	0.37 to 10.3	0.431
CT severity index: ≥8 vs <8	1.07	0.18 to 6.20	0.943
ASA: III/IV vs I/II	2.80	0.63 to 12.4	0.174
Time to LAMS removal: >4 vs ≤4 weeks	4.93	1.27 to 19.1	0.021
Reverse stepwise multivariate logistic regression analysis: Outcomevariable=AllLAMS-associated adverse events
PFC size: ≤7 vs >7 cm	4.33	1.10 to 17.0	0.036
Time to LAMS removal: >4 vs ≤4 weeks	4.60	1.30 to 16.3	0.018
Multiplepenalisedlogistic regression with Firth’s correction: Outcomevariable=LAMSassociated bleeding only
Age: ≥60 vs <60 years	1.14	0.24 to 5.37	0.866
Gender: Male vs Female	0.34	0.07 to 1.74	0.197
Race: Caucasian vs Non-Caucasian	11.1	0.32 to 382.9	0.182
PFC type: Necrotic collection vs Pseudocyst	0.25	0.02 to 3.12	0.283
PFC size: ≤7 vs >7 cm	42.4	2.28 to 787.8	0.012
PFC location: Tail involved vs Tail not involved	0.96	0.10 to 9.07	0.975
Degree of necrosis: ≤40 vs >40%	1.25	0.23 to 6.83	0.795
Route of drainage: Proximal stomach vs Other	5.76	0.79 to 41.9	0.084
CT severity index: ≥8 vs <8	2.75	0.30 to 25.5	0.372
ASA: III/IV vs I/II	3.35	0.56 to 20.1	0.186
Time to LAMS removal: >4 vs ≤4 weeks	1.54	0.35 to 6.78	0.566

ASA, American Society of Anesthesiologists; LAMS, lumen-apposing metal stent; PFC, pancreatic fluid collection.