Table 1

Characteristics of patients at the trial baseline

OverallPlacebo30 g FMT60 g FMTP
All patients164555455
Age, years39.9±9.041.2±13.739.2±12.439.3±13.20.672
Sex, female/male133/3247/840/1446/90.189
IBS-D63212220
IBS-C622220200.989
IBS-M39121314
IBS-SSS score313.4±80.3315.2±77.1311.8±76.8313.9±87.30.975
Birmingham IBS-S score24.3±7.123.2±8.126.5±6.025.2±6.80.050
IBS-QoL score113.5±21.8117.8±19.7109.1±22.7113.4±22.40.117
SF-NDI score30.2±7.729.9±1.629.7±7.130.9±8.40.728
FAS score31.1±4.930.6±4.931.4±5.131.3±4.80.634
DI2.8±1.12.7±1.12.8±1.02.9±1.00.781
Patients with dysbiosis(64)(67)(57)(67)0.578
PPI medication59 (35.8)21 (38.2)20 (36.4)18 (32.7)0.810
Birth-control medication84 (50.9)25 (45.5)29 (52.7)30 (54.5)0.601
Antimigraine medication12 (7.3)3 (5.5)5 (9.1)4 (7.3)0.764
Medication against asthma/allergies18 (10.9)6 (10.9)7 (12.7)5 (9.1)0.829
Medication with levothyroxine3 (1.8)1 (1.8)0 (0)2 (3.6)0.361
Medication with heart/vascular drugs6 (3.6)3 (5.5)2 (3.6)1 (1.8)0.595
  • Data are mean±SD, n, n/n, (%) or n (%) values.

  • DI, dysbiosis index; FAS, Fatigue Assessment Scale; FMT, faecal microbiota transplantation; IBS, irritable bowel syndrome; IBS-QoL, IBS Quality of Life; IBS-SSS, IBS Severity Scoring System; PPI, proton-pump inhibitor; SF-NDI, Short-Form Nepean Dyspepsia Index.