Table 2

Incidence rates* and HRs of PD for the total sample and subgroups

Types of Analysis	Not exposed to GIIs			Exposed to GIIs			Cox regression (ref.: not exposed to GIIs)
Types of Analysis	Events	Person years	IR	Events	Person years	IR	Cr. HR	95% CI	Adj. HR	95% CI
Overall†	5020	1 704 049	2.95	1175	250 573	4.69	1.42	1.33 to 1.52	1.42	1.33 to 1.52
Men‡	2327	724 388	3.21	493	93 896	5.25	1.48	1.34 to 1.63	1.48	1.34 to 1.63
Women‡	2693	979 661	2.75	682	156 677	4.35	1.38	1.27 to 1.50	1.38	1.27 to 1.50
Age <70 years§	1062	862 501	1.23	162	114 127	1.42	1.17	0.99 to 1.38	1.17	0.99 to 1.38
Age ≥70 years§	3958	841 548	4.70	1013	136 446	7.42	1.25	1.04 to 1.49	1.25	1.04 to 1.49
Without COPD¶	4051	1 438 104	2.82	858	191 598	4.48	1.65	1.53 to 1.78	1.43	1.33 to 1.54
With COPD¶	969	265 945	3.64	317	58 975	5.38	1.51	1.33 to 1.72	1.40	1.23 to 1.59
Without SRC¶	4650	1 613 378	2.88	1065	230 044	4.63	1.66	1.55 to 1.78	1.40	1.35 to 1.55
With SRC¶	370	90 671	4.08	110	20 529	5.36	1.93	1.59 to 2.33	1.20	0.96 to 1.48

N=228 485; PD cases=6195.
*Per 1000 person years.
†HRs were adjusted for gender, age, diabetes mellitus, cerebrovascular diseases, hypertension, ischaemic heart diseases, hypercholesterolaemia, chronic obstructive pulmonary disease and intracranial injury.
‡HRs were adjusted for age, diabetes mellitus, cerebrovascular diseases, hypertension, ischaemic heart diseases, hypercholesterolaemia, chronic obstructive pulmonary disease and intracranial injury.
§HRs were adjusted for gender, diabetes mellitus, cerebrovascular diseases, hypertension, ischaemic heart diseases, hypercholesterolaemia, chronic obstructive pulmonary disease and intracranial injury.
¶HRs were adjusted for gender, age, diabetes mellitus, cerebrovascular diseases, hypertension, ischaemic heart diseases, hypercholesterolaemia and intracranial injury,
Adj. HR, adjusted HR; COPD, chronic obstructive pulmonary disease; Cr. HR, crude HR; GII, GI infections; IR, incidence rate; PD, Parkinson’s disease; SRC, smoking-related cancers.