Table 1

Cohort characteristics for the seven cohorts of samples included in this study

CohortOriginTypePreparationSample sizePathologyMean ageM:F ratio
DiscoveryPolypsInternal (S:CORT)BiopsyFresh/frozenn=54Adenoma67.01.00
A (DC-A)TCGA9ResectionFresh/frozenn=618Carcinoma (colon, rectum)66.41.15
B (DC-B)Genentech11ResectionFresh/frozenn=66Carcinoma (colon)NANA
PancancerTCGA17ResectionFresh/frozenn=10‚ÄČ542Carcinoma (non-colorectal)59.10.92
ValidationA (Val-A)Internal (S:CORT)ResectionFFPEn=348Carcinoma (colon, rectum)63.51.79
B (Val-B)Internal (S:CORT)BiopsyFFPEn=230Carcinoma (rectum)671.71
Clinical applicationInternalResectionFFPEn=63Carcinoma (rectum)70.41.63
  • FFPE, formalin-fixed paraffin embedded; NA, not available; S:CORT, Stratification in Colorectal Cancer.