Table 2

AUROC of the 29 best performing fibrosis-related parameters in the training and validation cohorts

Fibrosis-related parametersTraining cohort, AUROC (95% CI)Validation cohort, AUROC (95% CI)
VariablesRegion of interestF2–F4F3–F4F4F2–F4F3–F4F4
StrPerimeterOverall0.954(0.924 to 0.983)0.931(0.889 to 0.974)0.957(0.929 to 0.985)0.946(0.912 to 0.980)0.959(0.930 to 0.988)0.963(0.934 to 0.992)
NoLongStrOverall0.953(0.923 to 0.982)0.929(0.887 to 0.972)0.955(0.925 to 0.985)0.930(0.890 to 0.969)0.957(0.927 to 0.987)0.962(0.933 to 0.991)
StrAreaOverall0.952(0.925 to 0.979)0.931(0.892 to 0.969)0.957(0.928 to 0.987)0.956(0.925 to 0.987)0.955(0.924 to 0.986)0.952(0.918 to 0.986)
StrLengthOverall0.950(0.920 to 0.980)0.929(0.887 to 0.970)0.953(0.924 to 0.981)0.931(0.893 to 0.970)0.952(0.920 to 0.984)0.963(0.935 to 0.992)
StrWidthOverall0.948(0.917 to 0.979)0.926(0.883 to 0.969)0.957(0.930 to 0.984)0.930(0.891 to 0.968)0.951(0.918 to 0.984)0.964(0.935 to 0.992)
NoLongStrVPeri-vessel0.946(0.913 to 0.980)0.936(0.895 to 0.977)0.959(0.931 to 0.987)0.930(0.891 to 0.969)0.960(0.932 to 0.988)0.954(0.917 to 0.991)
StrLengthVPeri-vessel0.945(0.912 to 0.978)0.936(0.897 to 0.976)0.957(0.930 to 0.983)0.928(0.889 to 0.968)0.954(0.924 to 0.984)0.953(0.915 to 0.991)
AggOverall0.945(0.911 to 0.978)0.923(0.877 to 0.968)0.947(0.914 to 0.980)0.965(0.938 to 0.991)0.963(0.935 to 0.991)0.957(0.925 to 0.989)
CCOverall0.943(0.910 to 0.975)0.924(0.880 to 0.967)0.955(0.922 to 0.987)0.956(0.927 to 0.985)0.961(0.933 to 0.989)0.965(0.938 to 0.992)
StrWidthVPeri-vessel0.942(0.908 to 0.976)0.933(0.892 to 0.974)0.960(0.935 to 0.985)0.930(0.891 to 0.968)0.955(0.926 to 0.985)0.957(0.923 to 0.992)
StrAreaVAPeri-vessel0.940(0.906 to 0.975)0.935(0.895 to 0.975)0.949(0.918 to 0.980)0.933(0.892 to 0.975)0.943(0.899 to 0.988)0.929(0.867 to 0.991)
StrAreaVPeri-vessel0.940(0.906 to 0.973)0.936(0.900 to 0.972)0.958(0.929 to 0.986)0.941(0.905 to 0.976)0.951(0.916 to 0.985)0.938(0.891 to 0.985)
VAggPeri-vessel0.939(0.903 to 0.975)0.929(0.884 to 0.974)0.950(0.917 to 0.982)0.959(0.932 to 0.987)0.964(0.935 to 0.992)0.950(0.909 to 0.990)
NoXlinkOverall0.939(0.904 to 0.973)0.921(0.875 to 0.967)0.946(0.912 to 0.980)0.949(0.917 to 0.981)0.951(0.917 to 0.986)0.966(0.939 to 0.994)
VCCPeri-vessel0.935(0.900 to 0.971)0.930(0.888 to 0.971)0.958(0.927 to 0.989)0.954(0.925 to 0.983)0.965(0.940 to 0.990)0.959(0.928 to 0.990)
NoXlinkVPeri-vessel0.935(0.900 to 0.971)0.928(0.883 to 0.973)0.949(0.916 to 0.982)0.949(0.916 to 0.981)0.961(0.932 to 0.989)0.966(0.939 to 0.993)
NoStrVPeri-vessel0.935(0.900 to 0.970)0.930(0.888 to 0.971)0.951(0.923 to 0.979)0.910(0.865 to 0.956)0.946(0.912 to 0.980)0.957(0.924 to 0.990)
StrLengthVAPeri-vessel0.935(0.899 to 0.971)0.922(0.874 to 0.970)0.933(0.893 to 0.974)0.920(0.874 to 0.965)0.947(0.904 to 0.990)0.942(0.882 to 1.000)
StrEccentricityOverall0.935(0.901 to 0.969)0.918(0.875 to 0.962)0.945(0.914 to 0.975)0.910(0.864 to 0.956)0.940(0.902 to 0.978)0.962(0.933 to 0.990)
NoStrOverall0.934(0.900 to 0.968)0.918(0.874 to 0.962)0.945(0.914 to 0.975)0.910(0.864 to 0.956)0.940(0.902 to 0.978)0.962(0.933 to 0.990)
NoThickStrVPeri-vessel0.934(0.898 to 0.969)0.929(0.887 to 0.971)0.953(0.926 to 0.981)0.912(0.867 to 0.956)0.946(0.912 to 0.980)0.959(0.927 to 0.991)
NoThickStrPeri-vessel0.932(0.897 to 0.967)0.916(0.871 to 0.961)0.946(0.916 to 0.976)0.911(0.865 to 0.956)0.940(0.902 to 0.978)0.963(0.934 to 0.991)
StrSolidityOverall0.931(0.895 to 0.966)0.915(0.870 to 0.960)0.942(0.911 to 0.974)0.907(0.860 to 0.953)0.937(0.898 to 0.976)0.958(0.929 to 0.988)
NoLongStrVAPeri-vessel0.929(0.891 to 0.968)0.913(0.862 to 0.965)0.931(0.885 to 0.977)0.916(0.871 to 0.961)0.948(0.908 to 0.988)0.944(0.890 to 0.998)
NoShortStrVPeri-vessel0.928(0.891 to 0.964)0.922(0.880 to 0.965)0.943(0.913 to 0.974)0.900(0.852 to 0.949)0.934(0.894 to 0.974)0.954(0.920 to 0.988)
NoShortStrOverall0.926(0.889 to 0.962)0.910(0.864 to 0.955)0.935(0.901 to 0.969)0.902(0.853 to 0.950)0.934(0.893 to 0.974)0.961(0.931 to 0.990)
StrWidthVAPeri-vessel0.926(0.887 to 0.964)0.914(0.864 to 0.965)0.933(0.890 to 0.975)0.925(0.883 to 0.967)0.947(0.907 to 0.987)0.943(0.888 to 0.998)
NoThinStrVPeri-vessel0.923(0.885 to 0.961)0.917(0.874 to 0.960)0.929(0.892 to 0.966)0.892(0.837 to 0.946)0.936(0.896 to 0.975)0.942(0.902 to 0.983)
NoThinStrVAPeri-vessel0.901(0.858 to 0.944)0.897(0.845 to 0.950)0.883(0.821 to 0.945)0.876(0.816 to 0.937)0.924(0.872 to 0.977)0.934(0.870 to 0.997)
  • AUROC, area under the receiver-operating characteristics curve.