Demographic characteristics of patients with type 1 diabetic, type 2 diabetic and idiopathic gastroparesis in the CPRD
| Study variable | Type 1 diabetes | Type 2 diabetes | Idiopathic |
| (n=220) | (n=162) | (n=447) | |
| Sex, n (%) | |||
| Female | 133 (60.5) | 111 (68.5) | 273 (61.1) |
| Male | 87 (39.5) | 51 (31.5) | 174 (38.9) |
| Age at first gastroparesis diagnosis, years | |||
| Mean (SD) | 46.3 (16.1) | 62.6 (12.2) | 44.5 (21.7) |
| Ethnicity, n (%) | |||
| n | 119 | 97 | 230 |
| White | 108 (90.8) | 73 (75.3) | 191 (83.0) |
| Asian | 11 (9.2) | 17 (17.5) | 35 (15.2) |
| Other | 0 (0.0) | 7 (7.2) | 4 (1.7) |
| Body weight, kg | |||
| n | 181 | 150 | 214 |
| Mean (SD), kg | 75.4 (20.4) | 82.2 (21.3) | 69.2 (20.4) |
| BMI, kg/m2 | |||
| n | 179 | 150 | 199 |
| Mean (SD) | 26.4 (6.5) | 30.2 (7.0) | 26.3 (10.6) |
| Median (Q1, Q3) | 25.4 (22.2, 30.4) | 30.4 (25.5, 33.5) | 25.3 (21.1, 29.3) |
| BMI category, n (%) | |||
| n | 179 | 150 | 199 |
| Underweight (<18.5 kg/m2) | 14 (7.8) | 4 (2.7) | 20 (10.1) |
| Normal (18.5–<25 kg/m2) | 64 (35.8) | 29 (19.3) | 75 (37.7) |
| Overweight (25–<30 kg/m2) | 50 (27.9) | 37 (24.7) | 62 (31.2) |
| Class I obesity (30–<35 kg/m2) | 36 (20.1) | 51 (34.0) | 27 (13.6) |
| Class II obesity (35–<40 kg/m2) | 7 (3.9) | 16 (10.7) | 10 (5.0) |
| Class III obesity (≥40 kg/m2) | 8 (4.5) | 13 (8.7) | 5 (2.5) |
| HbA1c, mmol/mol | |||
| n | 185 | 145 | 11 |
| Mean (SD) | 72.9 (25.8) | 63.3 (21.8) | 36.7 (4.7) |
| Alcohol use, n (%) | |||
| Never | 30 (13.6) | 36 (22.2) | 61 (13.6) |
| Former | 46 (20.9) | 35 (21.6) | 23 (5.1) |
| Current | 115 (52.3) | 65 (40.1) | 236 (52.8) |
| Unknown | 29 (13.2) | 26 (16.0) | 127 (28.4) |
| Smoking status, n (%) | |||
| Never | 44 (20.0) | 31 (19.1) | 165 (36.9) |
| Former | 92 (41.8) | 91 (56.2) | 153 (34.2) |
| Current | 57 (25.9) | 24 (14.8) | 66 (14.8) |
| Unknown | 27 (12.3) | 16 (9.9) | 63 (14.1) |
| Duration of registration before index date, years | |||
| Mean (SD) | 8.9 (6.0) | 10.7 (6.0) | 8.4 (5.7) |
| Duration of follow-up post-index date, years | |||
| Mean (SD) | 4.3 (3.2) | 3.9 (2.7) | 5.2 (3.5) |
| Charlson Comorbidity Index | |||
| Mean (SD) | 3.4 (1.9) | 3.4 (2.0) | 0.7 (1.2) |
| Median (Q1, Q3) | 3.0 (2.0, 4.0) | 3.0 (2.0, 5.0) | 0.0 (0.0, 1.0) |
| Charlson Comorbidity Index category, n (%) | |||
| 0 | 0 (0.0) | 0 (0.0) | 266 (59.5) |
| 1–2 | 93 (42.3) | 66 (40.7) | 149 (33.3) |
| 3–4 | 78 (35.5) | 54 (33.3) | 27 (6.0) |
| >=5 | 49 (22.3) | 42 (25.9) | 5 (1.1) |
| Comorbidities, n(%) | |||
| Cancer | 12 (5.5) | 25 (15.4) | 40 (8.9) |
| Cerebrovascular disease | 28 (12.7) | 16 (9.9) | 11 (2.5) |
| Congestive heart failure | 12 (5.5) | 11 (6.8) | 6 (1.3) |
| Chronic pulmonary disease | 60 (27.3) | 53 (32.7) | 95 (21.3) |
| Dementia | 2 (0.9) | 4 (2.5) | 0 (0.0) |
| Diabetes with complications | 206 (93.6) | 102 (63.0) | 0 (0.0) |
| Diabetes | 14 (6.4) | 60 (37.0) | 0 (0.0) |
| Hemiplegia or paraplegia | 1 (0.5) | 2 (1.2) | 2 (0.4) |
| HIV/AIDS | 0 (0.0) | 1 (0.6) | 0 (0.0) |
| Myocardial infarction | 16 (7.3) | 8 (4.9) | 14 (3.1) |
| Mild liver disease | 6 (2.7) | 6 (3.7) | 5 (1.1) |
| Moderate or severe liver disease | 3 (1.4) | 1 (0.6) | 0 (0.0) |
| Metastatic solid tumour | 0 (0.0) | 1 (0.6) | 3 (0.7) |
| Peptic ulcer disease | 14 (6.4) | 13 (8.0) | 30 (6.7) |
| Peripheral vascular disease | 28 (12.7) | 16 (9.9) | 6 (1.3) |
| Renal disease | 58 (26.4) | 43 (26.5) | 18 (4.0) |
| Rheumatic disease | 15 (6.8) | 12 (7.4) | 14 (3.1) |
AIDS, acquired immunodeficiency syndrome; BMI, body mass index; CPRD, Clinical Practice Research Datalink; HbA1c, glycated haemoglobin; HIV, human immunodeficiency virus; SD, standard deviation.