Table 1

Identification of putative risk factors in patients with COVID-19 developing severe liver injury during hospitalisation

VariableUnivariable OR (95% CI)P valueMultivariable OR (95% CI)P value
Ritonavir5.24 (0.69 to 16.39)<0.0015.63 (2.86 to 18.63)<0.001
IL-6, pg/mL2.13 (1.08 to 3.21)<0.0012.21 (1.09 to 4.67)0.006
IL-10, pg/mL1.82 (1.03 to 2.85)0.0041.78 (1.08 to 3.12)0.014
CD4+ T cell, per μL2.90 (1.85 to 5.96)<0.0013.24 (1.05 to 6.38)<0.001
CD8+ T cell, per μL1.88 (1.03 to 3.15)0.005
CD4+ T/CD8+ T cell1.08 (0.99 to 1.35)0.163
CD3+ T cell, per μL0.43 (0.19 to 0.88)0.034
Neutrophil count, ×109/L1.11 (1.02 to 1.25)0.077
Monocyte count, ×109/L3.41 (1.05 to 17.99)0.106