Table 2

Sensitivity, specificity and accuracy of taste or smell alteration in the prediction of COVID-19

AuthorTaste/smell (case)Taste/smell (control)Sensitivity (%)Specificity (%)PPV (%)NPV (%)Accuracy (%)
Roland66% (95/145)27% (42/157)65 (57.4–72.8)73.2 (65.8–79.6)69.3 (61.1–76.5)69.7 (62.3–76.4)69.5 (64.1–74.5)
Yan-171%* (42/59)17%* (35/203)71 (58–81.3)82.8 (76.9–87.4)54.5 (43.4–65.3)90.8 (85.7–94.2)80.2 (74.9–84.5)
Beltrán-Corbellini39% (31/79)13% (5/40)39 (29.1–50.4)87.5 (73.3–94.7)86.1 (70.7–94.1)42.2 (32–53)55.5 (46.5–64.1)
Moein35% (21/60)0% (0/60)35 (24.1–47.8)99.2 (88.2–99.9)97.7 (72.3–99.9)60.6 (50.7–69.7)67.5 (58.6–75.3)
Clemency49% (110/225)15% (108/736)48.9 (42.4–55.4)85.3 (88.2–87.7)50.5 (43.9–57.0)84.5 (81.7–86.9)76.8 (74–79.4)
Menni65% (4668/7178)22% (2436/11223)65 (63.9–66.1)78.3 (77.5–79)65.7 (64.6–66.8)77.8 (77–78.5)73.1 (72.5–73.8)
Meta-analysis 54.8 (44.3–64.9) 81.7 (76.5–85.9) 65.2 (55.9–73.4) 73.9 (64.3–81.6) 71.8 (67.5–75.7)
  • References are shown in the online supplementary materials.

  • Variables in bold are the results of meta-analysis.

  • *Using data on taste alteration.

  • NPV, negative predictive value; PPV, positive predictive value.