Demographic data of the 83 nested case and control pairs
Cases | Controls | |
HLA genotype, n (%) | ||
DQ2/DQ2 | 29 (35) | 11 (13) |
DQ2/DQ8 | 39 (47) | 36 (43) |
DQ8/DQ8 | 11 (13) | 20 (24) |
DQ8/X | 4 (5) | 15 (19) |
Other (ineligible) | 1 (1) | |
Age at CDA, months | 31 (23, 46) | NA |
Developed CD during follow-up, n (%) | 28 (34) | NA |
With CD-FDR, n (%) | 6 (7) | 3 (4) |
Breastfeeding | ||
Ever breastfed, n (%) | 83 (100) | 83 (100) |
Breastfeeding stopped, months | 8 (5, 11) | 8 (4, 12) |
Gluten | ||
Age at introduction, months | 6 (5, 7) | 6 (5, 7) |
Total intake by 2 years of age (g) | 8.0 (5.4, 11.0) | 7.6 (5.0, 11.8) |
IA positivity, n (%) | 41 (49) | 15 (18) |
Prior to CDA, n (%) | 31 (37) | NA |
For continuous variables, the median (25th percentile, 75th percentile) is reported.
CD, coeliac disease; CDA, coeliac disease autoimmunity; CD-FDR, subject having a first degree relative with coeliac disease; IA, islet autoantibody; NA, not applicable.