Proportions of patients with IBS with moderate symptom severity (IBS-SSS total score between 175 and 300) and severe symptom (IBS-SSS total score of ≥300) at different time intervals after FMT
| Symptoms | Group | Baseline | 2 weeks | 1 month | 3 months |
| Moderate symptom severity | Placebo | 23 (42%) | 14 (26%) | 17 (31%) | 16 (29%) |
| 30 g FMT | 23 (43%) | 20 (37%) | 22 (41%) | 18 (33%) | |
| 60 g FMT | 22 (40%) | 5 (9%)*** | 7 (13%)** | 14 (26%) | |
| Severe symptoms | Placebo | 32 (58%) | 23 (42%) | 27 (49%) | 28 (51%) |
| 30 g FMT | 31 (57%) | 11 (20%)*** | 10 (19%)† | 9 (17%)† | |
| 60 g FMT | 33 (60%) | 27 (49%) | 18 (33%)** | 7 (13%)† |
Statistical analysis was performed by χ2 test.
Values expressed as number of patients (%).
**P<0.01, ***P<0.01 compared with placebo.
†P<0.0001 compared with baseline.
FMT, faecal microbiota transplantation; IBS-SSS, IBS Symptom Severity Score.