Table 1

Area under the curve with 95% CIs achieved by the imCMS classifier

CMS class	FOCUS n slides=510 n patients=278		TCGA n slides=431 n patients=430		GRAMPIAN n slides=265 n patients=144
							3×	12×	3×	12×	3×	12×
							CMS1	0.83 (0.78 to 0.87)	0.85 (0.81 to 0.89)	0.82 (0.77 to 0.89)	0.82 (0.76 to 0.88)	0.76 (0.65 to 0.85)	0.82 (0.75 to 0.92)
	CMS2	0.88 (0.85 to 0.92)	0.86 (0.83 to 0.91)	0.84 (0.81 to 0.88)	0.82 (0.78 to 0.86)	0.78 (0.72 to 0.83)	0.75 (0.71 to 0.82)
CMS3	0.93 (0.91 to 0.97)	0.9 (0.85 to 0.94)	0.75 (0.67 to 0.83)	0.74 (0.68 to 0.81)	0.81 (0.75 to 0.9)	0.79 (0.73 to 0.88)
CMS4	0.87 (0.83 to 0.9)	0.85 (0.82 to 0.89)	0.84 (0.79 to 0.88)	0.82 (0.77 to 0.87)	0.94 (0.9 to 0.98)	0.94 (0.91 to 0.99)
Macro-average	0.88 (0.86 to 0.9)	0.87 (0.84 to 0.89)	0.81 (0.78 to 0.84)	0.8 (0.77 to 0.83)	0.82 (0.78 to 0.87)	0.83 (0.79 to 0.86)

CMS, consensus molecular subtype; imCMS, image-based consensus molecular subtype; TCGA, The Cancer Genome Atlas.