Table 3

mMED score and risk of Crohn’s disease according to selected Strata

CasesPerson-yearsMV-adjusted HR, 95% CI*Pinteraction
Sex
 Male99749 5310.32 (0.11 to 0.89)0.78
 Female65660 6370.50 (0.21 to 1.21)
 Age at start of follow-up
 <60 years101773 6220.45 (0.21 to 0.97)0.84
 ≥60 years63636 5460.31 (0.09 to 1.07)
Body mass index†
 <25 kg/m2 79677 7770.32 (0.13 to 0.79)0.52
 ≥25 kg/m2 85732 3910.56 (0.22 to 1.38)
Education
 Primary school120979 3530.45 (0.20 to 1.02)0.99
 High school20162 9810.49 (0.09 to 2.57)
 University24267 8340.46 (0.11 to 1.99)
Physical activity†
 <median77547 9560.33 (0.13 to 0.83)0.82
 ≥median56558 8950.61 (0.21 to 1.78)
Smoking†
 Never smoker60623 2660.83 (0.35 to 1.95)0.55
 Ever smoker101765 6270.17 (0.05 to 0.57)
  • *Comparing the extremes of mMED score quartiles. Models are adjusted for age (years), cohort (sex), body mass index, smoking (never, past and current) and total caloric intake.

  • †Missing data on these variables were not included or imputed for these analyses.

  • mMED, modified Mediterranean diet; MV, multivariable.