Table 2

mMED score and risk of Crohn’s disease and UC

mMED scorePtrend*
(0–2)
(n=22 237)
(3–4)
(n=36 951)
(5)
(n=13 630)
(6–8)
(n=10 329)
Person-years of follow-up361 082624 597238 698185 790
Crohn’s disease
 Number of cases56672912
 Age-adjusted, HR (95% CI)1.00.70 (0.49–0.99)0.78 (0.50–1.23)0.42 (0.22–0.78)0.02
 MV-adjusted, HR (95% CI)†1.00.69 (0.48–0.99)0.78 (0.49–1.24)0.42 (0.22–0.80)0.03
UC
 Number of cases841937444
 Age-adjusted, HR (95% CI)1.01.34 (1.03–1.73)1.33 (0.98–1.82)1.02 (0.71–1.46)0.81
 MV-adjusted, HR (95% CI)†1.01.35 (1.04–1.76)1.37 (0.99–1.90)1.08 (0.74–1.58)0.61
  • *Ptrend was calculated using the median value for each category.

  • †Models are adjusted for cohort (sex), age (years), education (primary school, high school and education), body mass index, smoking (never, past and current) and total caloric intake.

  • mMED, modified Mediterranean diet; MV, multivariable.