Table 1

Frequency of the most common deleteriously mutated genes in familial pancreatic cancer

GeneZhen et al44 (n=515)Roberts et al22 (n=166)Takai et al45 (n=54)Mutation prevalence (%)
BRCA219n.a.33.9
ATMn.a.422.7
CDKN2A13n.a.n.a.2.5
BRCA16n.a.n.a.1.2
PALB23n.a.20.9
  • Mutations data were analysed from three familial pancreatic cancer cohorts (735 samples).

  • n.a., not applicable.