Multivariable negative binomial regression model for antibiotic-treated infections (n=647)
| Univariable analyses | Multivariable analysis | |||||
| IRR | 95% CI | P value | aIRR | 95% CI | P value | |
| Anti-TNF-α monotherapy | 1.25 | 0.94 to 1.68 | 0.83 | 0.66 | 0.45 to 0.98 | 0.04 |
| Thiopurine monotherapy | 1.10 | 0.87 to 1.40 | 0.41 | 1.04 | 0.78 to 1.38 | 0.81 |
| Anti-TNF-α and thiopurine | 1.05 | 0.69 to 1.60 | 0.13 | 0.74 | 0.45 to 1.22 | 0.24 |
| Systemic corticosteroids | 1.09 | 0.85 to 1.40 | 0.49 | |||
| ICP | 1.60 | 0.82 to 3.13 | 0.17 | |||
| Smoking during pregnancy | 2.15 | 1.38 to 3.34 | <0.01 | 1.90 | 1.19 to 3.04 | <0.01 |
| Disease activity | 1.08 | 0.86 to 1.37 | 0.49 | |||
| Obstetric complications | 1.31 | 0.99 to 1.73 | 0.06 | 1.31 | 0.99 to 1.75 | 0.06 |
| Preterm birth | 1.23 | 0.94 to 1.61 | 0.14 | |||
| Daycare attendance | 0.89 | 0.66 to 1.21 | 0.47 | |||
| Breast feeding (>1 month) | 0.84 | 0.69 to 1.02 | 0.08 | 0.70 | 0.54 to 0.90 | <0.01 |
aIRR, Adjusted Incidence Rate Ratio; ICP, intrahepatic cholestasis of pregnancy; IRR, incidence rate ratio; TNF, tumour necrosis factor.