Baseline characteristics
| Variable | Measure | Autologous group (n=10) | Allogenic group (n=10) | P value |
| Sex (M:F) | Amount | 8:2 | 8:2 | 0.92 |
| Age (at diagnosis, years) | Mean | 25.0±3.5 | 24.3±5.4 | 0.73 |
| Weight (kg) | Mean | 75.0±13.0 | 71.0±10.9 | 0.46 |
| BMI (kg/m²) | Mean | 23.0±2.0 | 21.8±2.5 | 0.24 |
| Insulin use per day (IU) | Mean | 37±13 | 30±15 | 0.26 |
| Daily insulin use (IU/kg/day) | Mean | 0.49±0.13 | 0.43±0.24 | 0.55 |
| HbA1c (mmol/mol) | Median | 78 (66–90) | 78.5 (67–90) | 0.68 |
| Fasting C peptide (pmol/L) | Mean | 319±118 | 327±89 | 0.86 |
| Microalbumin/creat ratio (mg/mmol) | Median | 0.38 (0.34–0.41) | 0.84 (-0.59–2.26) | 0.31 |
| C peptide AUC (mmol/L/min) | Mean | 77±21 | 78±33 | 0.92 |
| Anti-GAD (U/mL) | Median | 110 (46–173) | 103 (57–149) | 0.85 |
| Anti-IA2 (U/mL) | Median | 696 (291–1094) | 623 (345–901) | 0.87 |
| Ketoacidosis (DKA) at diagnosis | Amount | 4/10 | 4/10 | 0.92 |
| CRP (mg/L) | Median | 0.8 (-20–22) | 0.7 (-13–15) | 0.83 |
| Leukocytes (×109/L) | Mean | 5.7±2.5 | 6.0±1.3 | 0.71 |
| Faecal calprotectin (mg/kg) | Median | 42 (21–63) | 26 (12–40) | 0.15 |
| Total cholesterol (mmol/L) | Mean | 4.7±1.0 | 4.4±0.37 | 0.39 |
| HDL-c (mmol/L) | Mean | 1.41±0.31 | 1.58±0.43 | 0.34 |
| LDL-c (mmol/L) | Mean | 2.90±0.89 | 2.46±0.37 | 0.16 |
| Triglycerides (mmol/L) | Mean | 0.86±0.47 | 0.81±0.41 | 0.78 |
| Total caloric intake (kcal/day) | Mean | 1999±548 | 2051±512 | 0.83 |
| Fat intake (g/day) | Mean | 78±23 | 123±74 | 0.09 |
| Sat. fat intake (g/day) | Mean | 45±55 | 64±70 | 0.51 |
| Protein intake (g/day) | Mean | 124±73 | 99±35 | 0.34 |
| Carbohydrate intake (g/day) | Mean | 176±92 | 220±143 | 0.41 |
| Fibre intake (g/day) | Mean | 27±12 | 27±8 | 0.97 |
For normally distributed parameters, the mean is shown ±SD, and p values were calculated using a Student’s t-test and for not normally distributed parameters, the median with IQR (P25–P75) is shown, and the p value was calculated using Mann-Whitney U test.
Anti-GAD, antiglutamic acid decarboxylase; anti-IA2, anti-islet antigen 2; AUC, area under the curve; BMI, body mass index; CRP, C-reactive protein; DKA, diabetic ketoacidosis; HbA1c, hemoglobin A1c; HDL, high-density protein cholesterol; LDL, low-density protein cholesterol.