Table 1

Baseline characteristics

VariableMeasureAutologous group (n=10)Allogenic group (n=10)P value
Sex (M:F)Amount8:28:20.92
Age (at diagnosis, years)Mean25.0±3.524.3±5.40.73
Weight (kg)Mean75.0±13.071.0±10.90.46
BMI (kg/m²)Mean23.0±2.021.8±2.50.24
Insulin use per day (IU)Mean37±1330±150.26
Daily insulin use (IU/kg/day)Mean0.49±0.130.43±0.240.55
HbA1c (mmol/mol)Median78 (66–90)78.5 (67–90)0.68
Fasting C peptide (pmol/L)Mean319±118327±890.86
ratio (mg/mmol)
Median0.38 (0.34–0.41)0.84 (-0.59–2.26)0.31
C peptide AUC (mmol/L/min)Mean77±2178±330.92
Anti-GAD (U/mL)Median110 (46–173)103 (57–149)0.85
Anti-IA2 (U/mL)Median696 (291–1094)623 (345–901)0.87
Ketoacidosis (DKA) at diagnosisAmount4/104/100.92
CRP (mg/L)Median0.8 (-20–22)0.7 (-13–15)0.83
Leukocytes (×109/L)Mean5.7±2.56.0±1.30.71
Faecal calprotectin (mg/kg)Median42 (21–63)26 (12–40)0.15
Total cholesterol (mmol/L)Mean4.7±1.04.4±0.370.39
HDL-c (mmol/L)Mean1.41±0.311.58±0.430.34
LDL-c (mmol/L)Mean2.90±0.892.46±0.370.16
Triglycerides (mmol/L)Mean0.86±0.470.81±0.410.78
Total caloric intake (kcal/day)Mean1999±5482051±5120.83
Fat intake (g/day)Mean78±23123±740.09
Sat. fat intake (g/day)Mean45±5564±700.51
Protein intake (g/day)Mean124±7399±350.34
Carbohydrate intake (g/day)Mean176±92220±1430.41
Fibre intake (g/day)Mean27±1227±80.97
  • For normally distributed parameters, the mean is shown ±SD, and p values were calculated using a Student’s t-test and for not normally distributed parameters, the median with IQR (P25–P75) is shown, and the p value was calculated using Mann-Whitney U test.

  • Anti-GAD, antiglutamic acid decarboxylase; anti-IA2, anti-islet antigen 2; AUC, area under the curve; BMI, body mass index; CRP, C-reactive protein; DKA, diabetic ketoacidosis; HbA1c, hemoglobin A1c; HDL, high-density protein cholesterol; LDL, low-density protein cholesterol.