Test | Baseline | 6 months | 12 months | ||||||

Auto (n=10) | Allo (n=10) | P value | Auto (n=10) | Allo (n=10) | P value | Auto (n=10) | Allo (n=10) | P value | |

C peptide, fasting (pmol/L) | 319±118 | 327±89 | 0.86 | 380±136 | 283±114 | 0.1 | 348±115 | 202±85 | 0.0045 |

C peptide, peak (t=90 min)(pmol/L) | 766±264 | 748±369 | 0.9 | 855±350 | 671±371 | 0.27 | 805±255 | 511±342 | 0.043 |

C peptide, AUC (mmol/L/min) | 77±21 | 78±33 | 0.92 | 89±35 | 69±36 | 0.24 | 85±27 | 53±33 | 0.032 |

Insulin dose (IU/kg/day) | 0.49±0.13 | 0.43±0.24 | 0.55 | 0.41±0.10 | 0.37±0.18 | 0.57 | 0.47±0.10 | 0.45±0.18 | 0.71 |

HbA1c (mmol/mol) | 78 (66–90) | 78.5 (67–90) | 0.68 | 45 (41–49) | 48.5 (41–56) | 0.41 | 46 (40–53) | 53.5 (44–63) | 0.19 |

The means±SD in the autologous and allogenic group at baseline, 6 and 12 months follow-up are shown. P values were calculated using the Student’s t-test. For HbA1c, the median and IQR (P25-P75) is shown, and the p value was calculated using a Mann-Whitney U test as it is not normally distributed. C peptide peak was measured at 90 min after ingestion of a mixed meal test. C peptide AUC designates the AUC of 120 min after the mixed meal with blood sampling at 0, 15, 30, 45, 60, 90 and 120 min.

AUC, area under the curve.