Quantification of HBV DNA integrations involving intron/exon human regions by droplet digital PCR
| Patient no. | Human genomic regions* | HBV regions | Number of HBV integrations/1000 hepatocytes† |
| 39 | ELAC2 intron-10 | HBx | 8 |
| 40 | IFITM1 intron-1 | HBx | 4 |
| IFITM1 intron-1 | Core | 5 | |
| 44 | NUP85 intron-3 | Pol | 3 |
| 62 | ANKRD52 intron-7 | Pol | 158 |
| ANKRD52 intron-7 | HBx | 157 | |
| 75 | AGBL5 intron-12 | HBx/Core | 7 |
| 83 | NR3C1 exon-5 | HBx | 4 |
| 84 | CYP2U1 intron-4 | HBx | 0.5 |
*The human genomic regions involved in HBV integrations were retrieved by ANNOVAR software.
†HBV integrations were quantified by digital droplet PCR assays.
HBx, hepatitis B X protein.