Table 2

Relative hepatic lipid content of the study groups from the CDAA murine model at 32 weeks

Parameter	CDAA WT vs CSAA WT		CDAA Ripk3^−/⁻ vs CDAA WT		CSAA Ripk3^−/⁻ vs CSAA WT		CDAA Ripk3^−/⁻ vs CSAA Ripk3^−/−
Parameter	Fold change	P value	Fold change	P value	Fold change	P value	Fold change	P value
FA	1.09	ns	1.05	ns	0.85	ns	1.34	0.04
SFA	1.22	ns	0.95	ns	0.80	0.06	1.45	0.01
MUFA	0.92	ns	1.22	ns	0.98	ns	1.14	ns
PUFA	1.12	ns	1.02	ns	0.81	ns	1.41	0.03
FA omega-3	1.06	ns	1.06	ns	0.74	0.03	1.52	0.01
FA omega-6	1.20	ns	1.90	ns	0.75	0.08	1.43	0.03
FA omega-9	0.90	ns	1.22	ns	1.08	ns	1.01	ns
DG	1.08	ns	1.42	<0.001	1.41	0.05	1.09	ns
Saturated DG	1.16	ns	1.69	<0.001	1.93	0.02	1.02	ns
TG	1.57	0.01	1.18	ns	1.13	ns	1.64	<0.001
Saturated TG	1.71	0.01	1.34	ns	1.57	0.01	1.46	0.04
ChoE	1.13	ns	1.27	ns	1.04	ns	1.37	0.02
PC	0.94	ns	0.92	ns	0.78	<0.001	1.10	ns
PE	1.42	0.01	0.91	ns	0.80	<0.001	1.62	0.001
Cer	1.01	ns	1.06	ns	0.83	0.04	1.27	0.01
SM	1.06	ns	0.96	ns	0.73	0.001	1.39	<0.001
MUFA+PUFA/SFA	0.86	0.04	1.14	0.03	1.08	ns	0.91	ns
PUFA/MUFA	1.22	0.04	0.80	0.03	0.81	0.02	1.20	0.03
Omega-6/omega-3	1.19	0.04	0.81	0.03	1.03	ns	0.94	ns
TG/DG	1.42	0.001	0.84	0.04	0.83	0.07	1.45	0.001
SM+DG/Cer+PC	1.12	0.01	1.19	0.001	1.21	0.01	1.10	ns
FA 16:0/18:2n-6	1.06	ns	0.99	ns	1.18	0.04	0.90	ns
FA 16:1n-7/16:0	0.58	ns	2.39	<0.001	1.72	0.01	0.94	ns
FA 18:0/16:0	1.14	ns	0.78	ns	0.97	ns	0.92	ns
FA 18:1n-9/18:0	0.77	ns	1.54	0.01	1.16	ns	1.02	ns
FA 18:3n-6/18:2n-6	1.66	<0.001	0.78	<0.01	1.03	ns	1.25	0.01
FA 20:4n-3/20:3n-3	0.69	0.001	1.50	<0.001	1.01	ns	1.02	ns
FA 20:5n-3/20:4n-3	1.56	0.01	0.71	0.02	0.93	ns	1.20	ns
FA 22:5n-3/20:5n-3	1.48	<0.01	0.87	ns	1.00	ns	1.28	<0.01

Cer, ceramides; ChoE, cholesteryl esters; DG, diglycerides; FA, fatty acids; MUFA, monounsaturated fatty acids; ns, non-significant; PC, phosphatidylcholines; PE, phosphatidylethanolamines; PUFA, polyunsaturated fatty acids; SFA, saturated fatty acids; SM, sphingomyelins; TG, triglycerides.