Table 2

Reasons for abandoning procedures in group A

CaseFindings at index procedureFindings at follow-up procedureComments on reasons for abandoning
1Location: sigmoid colon
Size: 35 mm
Type: LST-NG
SMSA: 11
Paris: IIa +c
Kudo: V
Biopsy: HGD
Outcome: for ER
Location: sigmoid
Size: 50 mm
Type: LST-NG
SMSA: 13
Paris: IIa +c
Kudo: V
Biopsies and CT findings in keeping with invasive carcinoma
Time interval between index and follow-up procedure: 25 weeks
15 mm interval growth and predicted submucosal invasion on repeat endoscopic inspection.
Surgery was felt to be the best therapeutic option
2Location : rectosigmoid (MRI described the lesion as non-invasive)
Size: 40 mm
Outcome: for colonoscopy
Location: rectosigmoid
Size: not described, malignant looking
Type: LST-NG
Paris: Is
Kudo: not described
Biopsies and CT findings in keeping with invasive carcinoma
Time interval between index and follow-up procedure: 16 weeks
Significant progression from polypoid lesion to invasive carcinoma in that time. Surgery was felt to be the best option
3Location : transverse colon size: 35 mm
Type: LST-NG
Paris: Is
Kudo: IIIs
Outcome : for ER
Location: transverse colon
Size: 45 mm
Type: LST-NG
Paris: IIa +c
Kudo: Vi tethered lesion Biopsies and CT show findings in keeping with invasive carcinoma
Time interval between index and follow-up procedure: 20 weeks
10 mm lesion growth but significant change in lesion characteristics (pit pattern and tethering). Therefore, surgery was deemed best option
4Location: rectosigmoid junction
Size: 35 mm
Type: semi pedunculated
Paris: Isp
Kudo: Vi
Outcome: for ER
Biopsy: LGD
Location: rectosigmoid
Size: 40 mm
Type: semipedunculated with nodule
Paris: Isp
Kudo: Vn
Thought to be malignant endoscopically. Biopsies showed HGD. MRI showed T2 lesion
Time interval between index and follow-up procedure: 14 weeks
Interval growth of 5 mm but lesion characteristics changed and ER abandoned. Surgery was deemed best option.
Surgical specimen confirmed poorly differentiated adenocarcinoma
5Location: Sigmoid Colon
Size : 12 mm
Type : LST-NG
Paris: Is
Kudo: IIIL
Outcome: Incompletely resected at index colonoscopy. Referred for complex polypectomy.
Location: Sigmoid
Size: not described as scarred and tethered
Type: LST-NG
Paris:Is
Kudo:Vn
Time interval between index and follow-up procedure: 20 weeks
Time interval between second colonoscopy and FTRD: 19 weeks.
FTRD was definitive treatment and lesion was completely excised
  • CT, computerised tomography of abdomen; ER, endoscopic resection; FTRD, full thickness resection with an over-the-scope clip device; HGD, high-grade dysplasia; Kudo, kudo pit pattern; LGD, low-grade dysplasia; LST-NG, lateral spreading lesion non-granular; MRI, magnetic resonance imaging; Paris, Paris classification; SMSA, size, morphology, site, access.