Performance characteristics for the biomarker signature
| Dataset (matrix) | Chronic pancreatitis versus control | ||
| Identification study (plasma) | First validation study (plasma) | Second validation study (serum) | |
| AUC (95 % CI) | 0.85 (0.79 to 0.91) | 0.85 (0.81 to 0.89) | 0.88 (0.81 to 0.95) |
| Sensitivity (LL – UL) | 0.71 (0.60–0.80) | 0.84 (0.77–0.89) | 0.78 (0.64–0.87) |
| Specificity (LL – UL) | 0.86 (0.77–0.92) | 0.66 (0.60–0.73) | 0.89 (0.78–0.95) |
| Cut-off | 0.479 | 0.479 | 0.479 |
AUC, area under the curve; LL, lower limit; UL, upper limit.