Table 2

Change from baseline in haemoglobin A1c (HbA1c) levels, liver MRI proton density fat fraction (MRI-PDFF) and weight (sham-treated modified intention-to-treat population)

ParameterEurope
N=37
Brazil
N=16
HbA1c levels at 24 weeks, mmol/moln=33n=15
−3.3 (10.9)−17.5 (9.8)
Liver MRI-PDFF >5% at baseline, n (%)28 (75.7)14 (87.5)
Absolute change in liver MRI-PDFF at 12 weeks, %−2.2 (4.3)−6.1 (7.8)
Weight at 24 weeks, kgn=34n=15
−1.4 (2.4)−2.1 (5.7)
  • Data are presented as median (IQR), unless otherwise indicated.