P value | HR | 95% CI | |
Able to tolerate thiopurines | |||
No | 0.0015 | 1.23 | 1.08 to 1.40 |
Yes | 1 | Referent | |
Treatment period | 0.92 | 1 | 0.96 to 1.05 |
Time from diagnosis to thiopurine initiation | 0.0001 | 0.99 | 0.98 to 0.99 |
Age at diagnosis | 0.0001 | 0.99 | 0.986 to 0.995 |
Gender | |||
Female | 0.05 | 1.11 | 1.00 to 1.24 |
Male | 1 | Referent | |
Smoking history | |||
No | 0.06 | 0.89 | 0.80 to 1.01 |
Yes | 1 | Referent | |
Disease location | |||
Ileal | 0.058 | 1.13 | 0.99 to 1.27 |
Colonic | <0.0001 | 0.5 | 0.43 to 0.58 |
Exclusive upper GI | 0.46 | 1.22 | 0.71 to 2.07 |
Ileocolonic | 1 | Referent | |
Perianal involvement | |||
No | <0.0001 | 0.52 | 0.47 to 0.59 |
Yes | 1 | Referent |
Significant p values shown in bold.
CD, Crohn’s disease.