Comparison of the baseline characteristics of all SARS-CoV-2-positive SARS-CoV-2-negative patients
| Variable | Category | SARS-CoV-2 negative | SARS-CoV-2 positive | P value | ||
| N | Summary | N | Summary | |||
| Number of patients* | 1628 | – | 149 | – | ||
| Age | – | 1618 | 54.5±18.1 | 147 | 59.9±17.2 | 0.001 |
| Sex | Female | 1620 | 786 (48.5%) | 148 | 55 (37.2%) | 0.009 |
| Male | 834 (51.5%) | 93 (62.8%) | ||||
| Ethnicity | White | 1358 | 1202 (88.5%) | 122 | 104 (85.3%) | 0.76 |
| Asian | 92 (6.8%) | 11 (9.0%) | ||||
| Black | 19 (1.4%) | 2 (1.6%) | ||||
| Mixed/Other | 45 (3.3%) | 5 (4.1%) | ||||
| Smoker | No | 1517 | 1043 (68.7%) | 132 | 100 (75.8%) | 0.05 |
| Yes | 474 (31.3%) | 32 (24.2%) | ||||
| Aetiology | Gallstones | 1628 | 696 (42.8%) | 149 | 60 (40.3%) | 0.37 |
| (dis)† | Alcohol | 434 (26.7%) | 28 (18.8%) | 0.04 | ||
| Idiopathic | 93 (5.7%) | 13 (8.7%) | 0.14 | |||
| Hereditary | 4 (0.3%) | 0 (0.0%) | ‡ | |||
| Post-ERCP | 43 (2.6%) | 3 (2.0%) | 0.64 | |||
| Post-EUS | 2 (0.1%) | 0 (0.0%) | ‡ | |||
| Steroid | 8 (0.5%) | 1 (0.7%) | 0.77 | |||
| Hypercalcaemia | 2 (0.1%) | 0 (0.0%) | ‡ | |||
| Hyperlipidaemia | 49 (3.0%) | 6 (4.0%) | 0.47 | |||
| Unknown | 315 (19.4%) | 37 (24.8%) | 0.08 | |||
| Other | 5 (0.3%) | 2 (1.3%) | 0.11 | |||
| Premorbid | 0 | 1534 | 945 (61.6%) | 125 | 58 (46.4%) | <0.001 |
| ECOG status | 1 | 373 (24.3%) | 31 (24.8%) | |||
| 2 | 153 (10.0%) | 17 (13.6%) | ||||
| 3 or 4 | 63 (4.1%) | 19 (15.2%) | ||||
| Ferritin | – | 77 | 246 (106, 742) | 20 | 910 (478, 1362) | 0.001 |
| LDH | – | 508 | 375 (242, 540) | 52 | 370 (276, 610) | 0.53 |
| Revised Atlanta | Mild | 1600 | 1244 (77.7%) | 146 | 71 (48.6%) | <0.001 |
| Criteria | Moderate-to-severe | 256 (16.0%) | 42 (28.8%) | |||
| Severe | 100 (6.3%) | 33 (22.6%) | ||||
| ARDS | No | 1387 | 56 (96.0%) | 140 | 121 (86.4%) | <0.001 |
| Yes | 56 (4.0%) | 19 (13.6%) | ||||
| Liver steatosis | No | 739 | 541 (73.2%) | 62 | 48 (77.4%) | 0.45 |
| Yes | 198 (26.8%) | 14 (22.6%) | ||||
| BMI | – | 845 | 27.4 (23.7, 32.1) | 91 | 28.4 (24.5, 33.1) | 0.41 |
| Necrosectomy | No | 1605 | 1585 (98.7%) | 145 | 137 (94.5%) | <0.001 |
| Yes | 20 (1.3%) | 8 (5.5%) | ||||
| Index | No | 1551 | 1467 (94.6%) | 145 | 144 (99.3%) | 0.02 |
| Cholecystectomy | Yes | 84 (5.4%) | 1 (0.7%) | |||
Summary statistics are mean±SD, median (p75–p25) or number (percentage). (*) Patients could have >1 aetiology so each aetiology considered as a separate variable.
*Includes all patients.
†Patients could have >1 aetiology so each aetiology considered as a separate variable.
‡Insufficient occurrences to enable a formal group comparison.
ARDS, acute respiratory distress syndrome; ECOG, Eastern Cooperative Oncology Group; LDH, lactate dehydrogenase.