Sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios for the Rome IV and Rome III criteria for irritable bowel syndrome, and by subtype for Rome IV
| Sensitivity (95% CI) | Specificity (95% CI) | Positive predictive value (95% CI) | Negative predictive value (95% CI) | Positive likelihood ratio (95% CI) | Negative likelihood ratio (95% CI) | |
| Rome IV criteria for IBS | 82.4% (78.6% to 85.8%) | 82.9% (74.8% to 89.2%) | 94.9% (92.3% to 96.9%) | 54.8% (47.2% to 62.3%) | 4.82 (3.30 to 7.28) | 0.21 (0.17 to 0.26) |
| Rome IV criteria for IBS with constipation | 77.9% (69.1% to 85.1%) | 97.0% (84.2% to 99.9%) | 98.9% (93.9% to 99.9%) | 56.1% (42.4% to 69.3%) | 25.7 (5.07 to 145) | 0.23 (0.16 to 0.32) |
| Rome IV criteria for IBS with diarrhoea | 81.7% (74.7% to 87.4%) | 60.5% (44.4% to 75.0%) | 88.4% (82.0% to 93.1%) | 47.3% (33.7% to 61.2%) | 2.07 (1.48 to 3.12) | 0.30 (0.20 to 0.46) |
| Rome IV criteria for IBS with mixed bowel habits | 84.8% (78.5% to 89.8%) | 92.0% (74.0% to 99.0%) | 98.6% (95.2% to 99.8%) | 46.9% (32.5% to 61.7%) | 10.6 (3.39 to 38.2) | 0.17 (0.11 to 0.24) |
| Rome III criteria for IBS | 85.8% (81.9% to 89.2%) | 65.0% (54.6% to 74.4%) | 90.4% (86.9% to 93.3%) | 54.3% (44.8% to 63.6%) | 2.45 (1.90 to 3.27) | 0.22 (0.16 to 0.29) |