Sensitivity (95% CI) | Specificity (95% CI) | Positive predictive value (95% CI) | Negative predictive value (95% CI) | Positive likelihood ratio (95% CI) | Negative likelihood ratio (95% CI) | |
Rome IV criteria for IBS plus abnormal levels of anxiety or depression | 60.8% (56.1% to 65.4%) | 84.6% (76.8% to 90.6%) | 93.8% (90.3% to 96.3%) | 36.3% (30.6% to 42.3%) | 3.95 (2.62 to 6.14) | 0.46 (0.40 to 0.53) |
Rome IV criteria for IBS plus high levels of extraintestinal symptom reporting | 24.1% (20.2% to 28.3%) | 95.7% (90.3% to 98.6%) | 95.6% (90.1% to 98.6%) | 24.6% (20.7% to 28.8%) | 5.64 (2.47 to 13.3) | 0.79 (0.74 to 0.85) |
Rome III criteria for IBS plus abnormal levels of anxiety or depression | 58.9% (53.9% to 63.8%) | 76.4% (67.2% to 84.1%) | 90.3% (86.0% to 93.6%) | 33.3% (27.4% to 39.6%) | 2.50 (1.79 to 3.60) | 0.54 (0.46 to 0.63) |
Rome III criteria for IBS plus high levels of extraintestinal symptom reporting | 20.3% (16.6% to 24.5%) | 93.9% (87.9% to 97.5%) | 92.6% (85.3% to 97. 0%) | 24.1% (20.2% to 28.3%) | 3.34 (1.65 to 6.97) | 0.85 (0.80 to 0.92) |