PANTHER pathway enrichment for differentially methylated genes in BrafW-5 vs Braf9–14 animals
| Pathway name | Fold enrichment | P value | FDR-corrected p value |
| Type-A | |||
| No significant pathway enrichment | |||
| Type-AB | |||
| Ionotropic glutamate receptor pathway | 5.9 | 1.34×10–4 | 5.56×10–3 |
| Cadherin signalling pathway | 4.88 | 2.81×10–8 | 4.66×10–6 |
| Wnt signalling pathway | 2.78 | 2.30×10–5 | 1.27×10–3 |
| Type-B | |||
| Ionotropic glutamate receptor pathway | 6.69 | 5.71×10–5 | 3.16×10–3 |
| Metabotropic glutamate receptor group III pathway | 5.65 | 6.56×10–5 | 2.72×10–3 |
| Heterotrimeric G-protein signalling pathway-Gi alpha and Gs | 4.29 | 2.94×10–6 | 4.87×10–4 |
| Heterotrimeric G-protein signalling pathway-Gq alpha and Go | 3.88 | 2.35×10–4 | 7.79×10–3 |
| Cadherin signalling pathway | 3.32 | 4.62×10–4 | 0.0128 |
Enrichment analysis was performed on genes with at least one differentially methylated CpG site mapping to the promoter region of the gene and is stratified for methylation type.