Predictors of 30-day mortality in 50 cirrhotic patients at SARS-CoV-2 diagnosis
Baseline variables | Category | Univariate analysis* | Multivariate analysis | ||
OR (95% CI) | P value | OR (95% CI) | P value | ||
Creatinine, mg/dL | Continuous | 2.80 (1.10 to 7.13) | 0.031 | ||
CPT score | A vs B/C | 0.20 (0.04 to 0.83) | 0.027 | ||
MELD | Continuous | 1.15 (1.03 to 1.29) | 0.009 | ||
CLIF-OF | Continuous | 1.74 (1.24 to 2.44) | 0.001 | 2.12 (1.23 to 3.65) | 0.006 |
Lung failure† | Moderate/severe vs absent/mild | 1.82 (1.08 to 3.06) | 0.022 | ||
CCI | Continuous | 2.91 (1.55 to 5.53) | 0.001 | 4.93 (1.46 to 16.60) | 0.010 |
Logistic regression analysis was used to identify factors associated with 30-day mortality and used a significance level of 0.05.
*Variables included in univariate analysis but not significantly associated to 30-day mortality: age, sex, bilirubin, albumin, aetiology of liver disease, diabetes mellitus, comorbidities, smoking history, hepatocellular carcinoma history.
†Moderate/severe lung failure PaO2/FiO2 ≤200 mm Hg.
CCI, Charlson Comorbidity Index; CLIF, European Foundation for the Study of Chronic Liver Failure Consortium; CPT, Child-Pugh-Turcotte; MELD, Model for End-Stage Liver Disease; OF, organ failure.