Statistical analysis results (linear model) of the signature metabolites (CP vs control)
| Dataset (matrix) | Identification study (plasma) | First validation study (plasma) | Second validation study (serum) | Importance of rank in the algorithm |
| Metabolite | Fold change (p value) | Fold change (p value) | Fold change (p value) | |
| Beta-carotene | 0.37 (6.8x10-8) | 0.38 (2.5x10-21) | 0.47 (0.00017) | 1 |
| Cryptoxanthin | 0.40 (8.8x10-8) | 0.38 (8.8x10-19) | 0.48 (0.00043) | 2 |
| Mannose | 1.47 (5.9x10-8) | 1.52 (3.9x10-29) | 2.80 (7.3x10-14) | 3 |
| Behenic acid (C22:0) | 0.72 (0.00024) | 0.67 (4.9x10-17) | 1.14 (0.10586) | 4 |
| Ceramide (d18:1, C24:1) | 1.27 (0.00016) | 1.28 (1.3x10-11) | 1.96 (6.7x10-13) | 5 |
| Indole-3-acetic acid | 0.63 (0.00086) | 0.62 (4.2x10-9) | 1.15 (0.33726) | 6 |
| Hippuric acid | 0.68 (0.039) | 0.49 (2.2x10-8) | 0.51 (0.00173) | 7 |
| N-acetylcytidine | 1.22 (0.0096) | 1.21 (2.3x10-5) | 2.36 (3.3x10-13) | 8 |
CP, chronic pancreatitis.