Sugar-sweetened beverage intake at age 13–18 years and risk of early-onset colorectal cancer
| <1 serving/week | 1 serving/week to <2 servings/day | ≥2 servings/day | Ptrend* | Each serving/day increase | |
| Person-years | 113 475 | 218 172 | 25 788 | ||
| No. of cases | 12 | 17 | 6 | ||
| Age- and energy-adjusted RR (95% CI) | 1 (reference) | 0.73 (0.34 to 1.58) | 2.43 (0.83 to 7.05) | 0.05 | 1.19 (0.92 to 1.54) |
| Multivariable RR (95% CI)† | 1 (reference) | 0.78 (0.36 to 1.73) | 3.41 (1.08 to 10.8) | 0.01 | 1.32 (1.00 to 1.75) |
One beverage serving is 8 oz.
*Calculated using the median of each category of beverage intake as a continuous variable.
†Additionally adjusted for race (white, non-white), height (continuous), body mass index at age 18 years (continuous), pack-years of smoking before age 20 years (continuous), intake of alcohol at age 15–17 years, red and processed meat, dietary fibre, total folate (from foods and supplements) and total calcium at age 13–18 years (all continuous), multivitamin use at age 13–18 years (yes, no) and physical activity at grade 9–12 (continuous).
RR, relative risk.