Table 5

Change of eight domains of quality of life after G-POEM measured with SF-36 questionnaire

Pre G-POEM (n=80/80, 100%)1 month (n=72/80, 90%)3 months (n=64/80, 80%)6 months (n=61/80, 76%)12 months (n=72/80, 90%)Difference between baseline and 12 monthsChange over the course of the studyChange between baseline and 12 months
Median (25th–75th percentiles)Median (25th–75th percentiles)Median (25th–75th percentiles)Median (25th–75th percentiles)Median (25th–75th percentiles)Mean (95% CI)P value*P value†
Physical functioning70 (35–91.25)77.5 (50–98.75)82.5 (45–95)85 (60–97.5)87.5 (56.25–100)−14.8 (−21.6 to −8)0.071 <0.001
Role limitation due to physical health0 (0–75)25 (0–100)50 (0–100)50 (0–100)62.5 (0–100)−14.5 (−25.3 to −3.7)0.085 0.008
Role limitation due to emotional problems66.7 (0–100)100 (0–100)100 (33.3–100)100 (33.3–100)100 (33.3–100)−14.2 (−26.7 to −1.6) <0.001 0.034
Vitality40 (20–55)50 (30–65)55 (27.5–70)50 (30–70)50 (30–75)−14 (−20.3 to −7.7) 0.002 <0.001
Mental health64 (52–80)68 (57–83)68 (56–83)72 (60–80)72 (56–88)−6.3 (−11.7 to −0.9) 0.004 0.038
Social functioning50 (25–62.5)56.25 (50–87.5)62.5 (38.125–87.5)75 (50–87.5)75 (37.5–100)−18.6 (−25.4 to −11.9) <0.001 <0.001
Bodily pain45 (22.5–67.5)57.5 (32.5–80)57.5 (33.125–85.625)57.5 (43.125–87.5)68.75 (45–90)−19.8 (−27.2 to −12.3)0.216 <0.001
General health37.5 (25–55)45 (30–61.25)45 (30–65)45 (27.5–65)40 (25–65)−5.3 (−10.4 to −0.3) 0.004 0.021
  • Bold indicates a statistically significant difference with a p-value less than 0.05.

  • *P values were determined from tests for trend using repeated-measures analysis whether the domains of quality of life improve over time (Friedman’s test).

  • †P values were determined by comparing 12 months and baseline values (Wilcoxon signed ranks test).

  • G-POEM, gastric per-oral endoscopic myotomy; SF-36, 36-Item Short Form.