Accuracy of current commonly used Helicobacter pylori diagnosis methods
| H. pylori diagnosis tests | Sensitivity | Specificity | Positive predictive value | Negative predictive value |
| Non-invasive tests | ||||
| 13C-UBT135 138 161 | 90.0%–96.0% | 94%–98.0% | 97.4%–99.2% | 90.8%–91.2% |
| 14C-UBT135 136 148 162 | 96%–97.3% | 91%–97.0% | 93.31%–96.8% | 94.3%–97.6% |
| Serum anti-H. pylori IgG antibody test142–144
Serum anti-H. pylori protein array UreB/CagA/VacA145 | 72.7%–90.0% 93.4%/95.4%/96.04% | 68.4%–100.0% 94.8%/94.4%/97.5% | 66.7%–100.0% N/A | 74.3%–83.3% N/A |
| HpSA ELISA test133 146–148 | 73.9%–95.0% | 86.8%–100.0% | 85%–100.0% | 76.5%–92.0% |
| Invasive tests | ||||
| RUT148 149 161 | 85.0%–99.0% | 92.4%–94.1% | 90.5%–97.4% | 86.5%–99.2% |
| Histology138 150 151 161 | 83%–95.5% | 95.4%–100.0% | 94.6%–100.0% | 88.6%–97.0% |
| Culture148 150 152 | 67.9%–96.0% | 79.4%–100.0% | 88.7%–100.0% | 50.9%–95.0% |
HpSA, Helicobacter pylori stool antigen test; N/A, not available; RUT, rapid urease test; UBT, urea breath test.