Baseline patient characteristics
| EFTP group (n=35) | Sham group (n=35) | P values | |
| Median age (y) | 35 (29–41) | 37 (29–45) | 0.401 |
|
Sex, n (%) Female | 10 (28.6%) | 10 (28.6%) | 1.000 |
| PPI use duration (y) | 2.0 (1.0–5.0) | 2.5 (1.5–3.5) | 0.855 |
| Hill’s grade of GE flap, n (%) | |||
| I | 16 (45.7) | 18 (51.4) | 0.746 |
| II | 6 (17.1) | 7 (20) | |
| III | 13 (37.1) | 10 (28.6) | |
| Oesophagitis LA grade, n (%) | |||
| Normal | 24 (68.6) | 25 (71.4) | 0.543 |
| A | 11 (31.4) | 9 (25.7) | |
| B | 0 (0) | 1 (2.9) | |
| Baseline median % time oesophageal pH <4 | 4.4 (2.0–8.7) | 2.7 (1.3–5.9) | 0.127 |
| DeMeester score | 15.1 (7.6–28.0) | 12.2 (6.8–21.4) | 0.447 |
| Total reflux episodes | 90 (65–115) | 92 (65–130) | 0.733 |
| Acid reflux episodes | 51 (33–73) | 40 (27–61) | 0.106 |
| Non acid reflux episodes | 34 (18–71) | 49 (25–77) | 0.264 |
| GERD HRQL total score | 40 (23–51) | 43 (30–50) | 0.492 |
| Heart Burn symptom score | 19 (12–26) | 18 (8–26) | 0.597 |
| Regurgitation symptom score | 21 (10–26) | 24 (19–28) | 0.076 |
All continuous data are expressed as median (IQR).
EFTP, endoscopic full-thickness plication; GE, gastro-oesophageal; GERD-HRQL, GERD health-related quality of life; LA, Los Angeles classification of erosive oesophagitis; PPI, proton pump inhibitors.