Table 3

Comparison of 24-hour pH impedance study results between endoscopic full-thickness plication (EFTP) and sham groups at 3 and 12 months after intervention

Parameter		EFTP	P value Baseline versus 3 and 12 months	Sham	P value Baseline versus 3 and 12 months	P value EFTP versus sham
Median % time oesophageal pH <4	Baseline	4.4 (2.0–8.7)		2.7 (1.3–5.9)		0.127
	3 months	3.6 (0.4–9.0)	0.422	3.5 (1.4–6.4)	0.915	0.833
	12 months	3.4 (0.6–5.5)	0.276	5.4 (2.0–9.0)	0.441	0.111
DeMeester Score	Baseline	15.1 (7.6–28.0)		12.2 (6.8–21.4)		0.447
	3 months	14.2 (1.7–29.3)	0.447	14.7 (6.2–20)	0.749	0.934
	12 months	21.5 (11.0–49.2)	0.231	20.1 (9.7–27.5)	0.343	0.504
Total reflux episodes	Baseline	90 (65–115)		92 (65–130)		0.733
	3 months	66 (46–92)	0.005	85 (61–122)	0.055	0.072
	12 months	54.5 (33–100)	0.122	120 (69.5–129)	0.859	0.051
Acid reflux episodes	Baseline	51 (33–73)		40 (27–61)		0.106
	3 months	34 (16–63)	0.063	40 (30–62)	0.933	0.414
	12 months	31.5 (17.5–73.5)	0.316	66 (47–69)	0.260	0.227
Non-acid reflux episodes	Baseline	34 (18–71)		49 (25–77)		0.264
	3 months	23 (12–42)	0.054	35 (21–70)	0.077	0.048
	12 months	11.5 (2.5–21.8)	0.038	50 (25.5–62.5)	0.214	0.005

All continuous data are expressed as median (IQR).