Table 3

Comparison of 24-hour pH impedance study results between endoscopic full-thickness plication (EFTP) and sham groups at 3 and 12 months after intervention

ParameterEFTPP value
Baseline versus 3 and 12 months
ShamP value
Baseline versus
3 and 12 months
P value
EFTP versus sham
Median % time oesophageal pH <4Baseline4.4 (2.0–8.7)2.7 (1.3–5.9)0.127
3 months3.6 (0.4–9.0)0.4223.5 (1.4–6.4)0.9150.833
12 months3.4 (0.6–5.5)0.2765.4 (2.0–9.0)0.4410.111
DeMeester ScoreBaseline15.1 (7.6–28.0)12.2 (6.8–21.4)0.447
3 months14.2 (1.7–29.3)0.44714.7 (6.2–20)0.7490.934
12 months21.5 (11.0–49.2)0.23120.1 (9.7–27.5)0.3430.504
Total reflux episodesBaseline90 (65–115)92 (65–130)0.733
3 months66 (46–92)0.00585 (61–122)0.0550.072
12 months54.5 (33–100)0.122120 (69.5–129)0.8590.051
Acid reflux episodesBaseline51 (33–73)40 (27–61)0.106
3 months34 (16–63)0.06340 (30–62)0.9330.414
12 months31.5 (17.5–73.5)0.31666 (47–69)0.2600.227
Non-acid reflux episodesBaseline34 (18–71)49 (25–77)0.264
3 months23 (12–42)0.05435 (21–70)0.0770.048
12 months11.5 (2.5–21.8)0.03850 (25.5–62.5)0.2140.005
  • All continuous data are expressed as median (IQR).