Characteristics of study participants by IBS subtype
| Characteristic | Constipation-predominant IBS (n=9) | Diarrhoea-predominant IBS (n=10) | P value |
| Age, median (min–max) | 39 (19–65) | 43 (19–65) | 0.92 |
| Gender, male/female | 2/7 | 2/8 | >0.99 |
| BMI (kg/m2), mean±SD | 26.2±5.7 | 35.0±7.1 | 0.009 |
| HADS-A, mean±SD | 6.8±6.3 | 5.6±3.7 | 0.62 |
| HADS-D, mean±SD | 2.8±3.1 | 3.6±2.4 | 0.34 |
| PHQ-12SS, mean±SD | 4.6±4.4 | 7.7±3.4 | 0.10 |
| Weekly bowel frequency, mean±SD | 7.7±3.0 | 12.4±5.0 | 0.02 |
| Weekly Bristol Stool Form Scale Score, mean±SD | 2.1±0.8 | 5.3±0.8 | 0.02 |
BMI, body mass index; HADS-A, Hospital Anxiety and Depression Scale-Anxiety subscale; HADS-D, Hospital Anxiety and Depression Scale-Depression subscale; PHQ-12SS, Patient Health Questionnaire-12 Somatic Symptom Scale.