Pathway name | Fold enrichment | FDR-corrected p value |
Alpha adrenergic receptor signalling pathway | 3.07 | 0.033 |
Alzheimer disease-presenilin pathway | 2.52 | 1.51×10–5 |
Ionotropic glutamate receptor pathway | 2.51 | 0.019 |
Alzheimer disease-amyloid secretase pathway | 2.42 | 7.90×10–3 |
Heterotrimeric G-protein signalling pathway-Gi alpha and Gs alpha | 2.07 | 3.52×10–4 |
Gonadotropin-releasing hormone receptor pathway | 2.04 | 1.42×10–5 |
Angiogenesis | 2 | 6.89×10–4 |
Heterotrimeric G-protein signalling pathway-Gq alpha and Go alpha | 1.96 | 9.78×10–3 |
Transforming growth factor-beta signalling pathway | 1.92 | 0.033 |
Platelet derived growth factor signalling pathway | 1.89 | 8.94×10–3 |
Cadherin signalling pathway | 1.88 | 7.37×10–3 |
Wnt signalling pathway | 1.82 | 7.34×10–5 |
Epidermal growth factor receptor signalling pathway | 1.76 | 0.040 |
Integrin signalling pathway | 1.7 | 0.018 |
Type-B CpGs were identified as those significantly associated with age in the Braf mutant intestine from weaning but not associated with age in wild-type animals. CpGs were assessed by regression analyses and pathway enrichment determined using the PANTHER enrichment tool.