Table 2

Prediction model coefficients*

	AN			CRC
	Adjusted OR	95% CI	P value	Adjusted OR	95% CI	P value
Age†	1.1	0.9 to 1.3	0.45	1.8	1.1 to 2.8	0.01
Male sex	1.3	1.3 to 1.4	<0.001	1.2	1 to 1.4	0.05
First F-Hb concentration, µg Hb/g faeces
0	Ref			Ref
0.1–9.9‡	2.8	2.6 to 3.1	<0.001	2.5	2.0 to 3.2	<0.001
10.0–19.9	4.2	3.7 to 4.7	<0.001	3.6	2.7 to 4.9	<0.001
20.0–29.9	5.7	4.8 to 6.7	<0.001	5.7	3.9 to 8.4	<0.001
30.0–39.9	6.6	5.4 to 8.0	<0.001	3.7	2.1 to 6.6	<0.001
40.0–46.9	9.4	7.5 to 11.7	<0.001	6.3	3.5 to 11.1	<0.001
Second F-Hb concentration, µg Hb/g faeces
0	Ref			Ref
0.1–9.9‡	4.8	4.3 to 5.3	<0.001	3.0	2.2 to 4.0	<0.001
10.0–19.9	6.2	5.5 to 7.0	<0.001	4.6	3.4 to 6.2	<0.001
20.0–29.9	7.9	6.8 to 9.1	<0.001	4.1	2.7 to 6.2	<0.001
30.0–39.9	8.0	6.7 to 9.5	<0.001	4.8	3.1 to 7.5	<0.001
40.0–46.9	8.6	7.0 to 10.5	<0.001	4.9	2.8 to 8.4	<0.001

ORs were derived using logistic regression and examined using Wald tests.
*Coefficients are obtained as log (OR). The (exponentiated) model intercepts for advanced neoplasia and CRC were 0.005 (95% CI 0.005 to 0.006) and 0.001 (95% CI 0.001 to 0.001).
†OR for continuous age represents the estimated relative increase in the detection of AN or CRC for every 10-year increase in age.
‡In multivariate analysis, positive F-Hb concentrations below the detection limit were combined in one category with concentrations just above that limit.
AN, advanced neoplasia; CRC, colorectal cancer ; F-Hb, faecal haemoglobin.