Statement 15: After failure of the first-line treatment with clarithromycin-containing triple or non-BQTs, and second-line treatment with fluoroquinolone-containing therapy, it is recommended to use the bismuth-based quadruple therapy. If bismuth is not available, high-dose PPI-amoxicillin dual or a rifabutin-containing regimen could be considered.
Agreement 84%	Grade B2