Table 1

Inclusion and exclusion criteria

Inclusion criteria
Age18–65 years
Clinical activityMild to moderate ulcerative colitis: SCCAI 3–9
Endoscopic activityUCEIS>1
Disease extentLeft-sided colitis/pancolitis
Permitted medications
Oral 5-ASAStable dose for >4 weeks
Azathioprine/6-MPStable dose for >3 months
Topical therapy (topical 5-ASA or topical steroid)Stable dose for >2 weeks
Oral steroid<20 mg prednisolone equivalent with mandatory taper of 5 mg/week
Anti-TNF monoclonal antibodyIf used more than 6 months back
OthersAgree to adhere to diet schedule
Gave written informed consent
Exclusion criteria
Disease activitySevere disease activity or acute severe ulcerative colitis
Patients requiring hospitalisation or surgery
Prohibited medications
Topical therapyIf used within 2 weeks
Antibiotic or probioticWithin 4 weeks of randomisation
OthersPatients with history of bowel surgery
Concomitant GI infection
Comorbid illnesses
  • 5-ASA, 5-aminosalicylic acid; 6-MP, 6-mercaptopurine; SCCAI, Simple Clinical Colitis Activity Index; TNF, tumour necrosis factor; UCEIS, Ulcerative Colitis Endoscopic Index of Severity.