Table 1

Patient information

GroupImmune tolerantImmune activationARCRHC
Cases65336
Age (years)34 (21–55)29 (25–45)37 (28–45)47 (45–49)52 (33–66)
Sex (M/F)4/24/12/13/04/2
Time since HBV diagnosis (years)14.7 (1.5–27.0)20 (10–20)<0.510 (1–20)NA
HBsAg level (IU/mL)40 636 (5652–69 050)7881 (833.2–32 970.0)783 (0–1293)<0.05NA
HBV DNA level (log10 IU/mL)8.328 (8–8.88)6.761 (5.29–8)0.9783 (0–2.935)LDLNA
ALT (U/L)36.1 (20–45.7)232.2 (60–424)108 (25–192)18.67 (13–22)20.8 (11–31)
AST (U/L)28.7 (19–42)91.2 (34–129)44 (21–58)19 (16–24)19 (15–27)
  • ALT, alanine aminotransferase; AR, acute recovery; AST, aspartate transaminase; CR, chronic resolved ; F, female; HBsAg, HBV surface antigen; HC, healthy control; LDL, lower detection limit; M, male; NA, not applicable.