Table 2

GRADE quality ratings

LevelDescription
HighFurther research is very unlikely to change our confidence in the estimate of effect
ModerateFurther research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate
LowFurther research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate
Very lowAny estimate of effect is very uncertain