Table 3

Demographics of adults persons with CF without prior transplant and HEV serostatus

HEV seropositive (n=16)
N (%)
HEV seronegative (n=67)
N (%)
Characteristic
Female sex8 (50)28 (42)
Median age, years (IQR)30.9 (24.9–37.5)32.0 (25.0–39.3)
Median body mass index, median (IQR, kg/m2)23.2 (22.0–24.1)23.3 (20.9–25.1)
Rural postal code5 (31)22 (33)
Lung disease stage**
 Mild8 (50)36 (54)
 Moderate5 (31)21 (31)
 Severe3 (19)10 (15)
Genotype
 ΔF508 homozygous10 (63)40 (60)
 ΔF508 heterozygous5 (31)21 (31)
Other1 (6)6 (9)
CF comorbidities
 Pancreatic insufficiency16 (100)60 (90)
 CF liver disease3 (19)16 (24)
 GORD9 (56)41 (61)
 Distal intestinal obstruction syndrome14 (88)42 (63)
 CF arthropathy3 (19)9 (13)
 Sinus disease (polyps or nasal congestion)15 (94)55 (82)
Respiratory infections
Pseudomonas aeruginosa9 (56)39 (58)
 Methicillin-susceptible Staphylococcus aureus6 (39)27 (40)
 Methicillin-resistant S. aureus1 (6)5 (8)
 Other†4 (25)15 (22)
  • *Definitions of lung stage based on forced expiratory volume in 1 s; mild ≥70%, moderate ≥40% to <70%, severe <40%.

  • †Other bacterial species include Escherichia coli, Enterobacter cloacae, Serratia marcescens, group C Streptococcus, Stenotrophomonas maltophilia.

  • CF, cystic fibrosis; HEV, hepatitis E virus.