6-mercaptopurine

There is still a place for optimised thiopurine therapy in IBD
Femke Crouwel, Hans J C Buiter, Nanne K H de Boer

Gut Nov 2021, 70 (11) 2207; DOI: 10.1136/gutjnl-2020-323481
Thiopurine monotherapy is effective in ulcerative colitis but significantly less so in Crohn’s disease: long-term outcomes for 11 928 patients in the UK inflammatory bowel disease bioresource
Evangelos Stournaras, Wendi Qian, Apostolos Pappas, You Yi Hong, Rasha Shawky, UK IBD BioResource Investigators, Tim Raine, Miles Parkes

Gut Apr 2021, 70 (4) 677-686; DOI: 10.1136/gutjnl-2019-320185
Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide
P W Lowry, C L Franklin, A L Weaver, C L Szumlanski, D C Mays, E V Loftus, W J Tremaine, J J Lipsky, R M Weinshilboum, W J Sandborn

Gut Nov 2001, 49 (5) 656-664; DOI: 10.1136/gut.49.5.656
Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease
P W Lowry, C L Franklin, A L Weaver, M Gennett Pike, D C Mays, W J Tremaine, J J Lipsky, W J Sandborn

Gut Nov 2001, 49 (5) 665-670; DOI: 10.1136/gut.49.5.665
5-Aminosalicylic acid prevents oxidant mediated damage of glyceraldehyde-3-phosphate dehydrogenase in colon epithelial cells
S M McKenzie, W F Doe, G D Buffinton

Gut Feb 1999, 44 (2) 180-185; DOI: 10.1136/gut.44.2.180
Impact of thiopurines on the natural history and surgical outcome of ulcerative colitis: a cohort study
Carl Eriksson, Sara Rundquist, Yang Cao, Scott Montgomery, Jonas Halfvarson

Gut Apr 2019, 68 (4) 623-632; DOI: 10.1136/gutjnl-2017-315521
Role of thiopurines as disease-modifying agents in Crohn’s disease
Jonathan Blackwell, Sonia Saxena, Richard C Pollok

Gut Dec 2018, 67 (12) 2229-2230; DOI: 10.1136/gutjnl-2017-315840
Microbiota: relevant player in thiopurine metabolisation?
Imke Atreya, Markus F Neurath

Gut Jan 2017, 66 (1) 1-3; DOI: 10.1136/gutjnl-2016-312450
CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated?
Jonas Rosendahl, Olfert Landt, Jana Bernadova, Peter Kovacs, Niels Teich, Hans Bödeker, Volker Keim, Claudia Ruffert, Joachim Mössner, Andreas Kage, Michael Stumvoll, David Groneberg, Renate Krüger, Werner Luck, Matthias Treiber, Michael Becker, Heiko Witt

Gut Apr 2013, 62 (4) 582-592; DOI: 10.1136/gutjnl-2011-300645
Reassuring results on birth outcomes in children fathered by men treated with azathioprine/6-mercaptopurine within 3 months before conception: a nationwide cohort study
B M Nørgård, B Magnussen, M D Larsen, S Friedman

Gut Oct 2017, 66 (10) 1761-1766; DOI: 10.1136/gutjnl-2016-312123

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